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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM3
All Species:
24.24
Human Site:
T4
Identified Species:
38.1
UniProt:
P25205
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25205
NP_002379.2
808
90981
T4
_
_
_
_
M
A
G
T
V
V
L
D
D
V
E
Chimpanzee
Pan troglodytes
XP_001151750
808
90957
T4
_
_
_
_
M
A
G
T
V
V
L
D
D
V
E
Rhesus Macaque
Macaca mulatta
XP_001106966
808
90990
T4
_
_
_
_
M
A
G
T
V
V
L
D
D
V
E
Dog
Lupus familis
XP_538960
916
102667
T112
V
A
A
G
M
A
G
T
V
V
L
D
D
V
E
Cat
Felis silvestris
Mouse
Mus musculus
P25206
812
91528
T4
_
_
_
_
M
A
G
T
V
V
L
D
D
V
E
Rat
Rattus norvegicus
XP_001070728
813
91641
T4
_
_
_
_
M
A
G
T
V
V
L
D
D
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMN2
812
91233
A5
_
_
_
M
A
A
P
A
G
G
L
G
D
A
E
Frog
Xenopus laevis
Q7ZXZ0
806
90528
V4
_
_
_
_
M
A
A
V
T
E
L
D
D
Q
E
Zebra Danio
Brachydanio rerio
NP_997732
807
90502
G29
L
D
D
D
Q
D
Q
G
I
Y
Q
S
K
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511048
819
90900
E4
_
_
_
_
M
A
H
E
G
E
Q
F
I
K
D
Honey Bee
Apis mellifera
XP_625020
811
91329
D5
_
_
_
M
D
I
I
D
R
D
Q
R
L
E
E
Nematode Worm
Caenorhab. elegans
Q21902
759
84917
I9
S
N
L
D
N
P
G
I
Y
Y
Q
E
R
F
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q43704
768
85163
M8
M
E
I
N
E
E
A
M
A
A
H
K
R
A
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FL33
776
86338
S21
D
F
I
Q
F
L
D
S
M
Y
M
E
E
I
K
Baker's Yeast
Sacchar. cerevisiae
P24279
971
107499
A53
Q
V
Y
N
S
N
N
A
A
N
Y
N
D
D
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.5
86
N.A.
92.9
93.3
N.A.
N.A.
81.4
80.1
75.9
N.A.
62.5
62.7
30.8
N.A.
Protein Similarity:
100
99.8
100
87.2
N.A.
96.6
97
N.A.
N.A.
92
90.7
88.1
N.A.
80
78.6
49.5
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
100
100
N.A.
N.A.
33.3
54.5
6.6
N.A.
18.1
8.3
6.6
N.A.
P-Site Similarity:
100
100
100
80
N.A.
100
100
N.A.
N.A.
33.3
54.5
13.3
N.A.
27.2
8.3
13.3
N.A.
Percent
Protein Identity:
N.A.
47.6
N.A.
49.3
39.8
N.A.
Protein Similarity:
N.A.
66
N.A.
68.1
54.7
N.A.
P-Site Identity:
N.A.
0
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
53.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
7
60
14
14
14
7
0
0
0
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
7
14
7
7
7
7
0
7
0
47
60
7
7
% D
% Glu:
0
7
0
0
7
7
0
7
0
14
0
14
7
7
60
% E
% Phe:
0
7
0
0
7
0
0
0
0
0
0
7
0
7
14
% F
% Gly:
0
0
0
7
0
0
47
7
14
7
0
7
0
0
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
7
0
0
0
0
% H
% Ile:
0
0
14
0
0
7
7
7
7
0
0
0
7
7
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
7
7
7
7
% K
% Leu:
7
0
7
0
0
7
0
0
0
0
54
0
7
0
0
% L
% Met:
7
0
0
14
54
0
0
7
7
0
7
0
0
0
0
% M
% Asn:
0
7
0
14
7
7
7
0
0
7
0
7
0
0
0
% N
% Pro:
0
0
0
0
0
7
7
0
0
0
0
0
0
0
0
% P
% Gln:
7
0
0
7
7
0
7
0
0
0
27
0
0
7
7
% Q
% Arg:
0
0
0
0
0
0
0
0
7
0
0
7
14
0
7
% R
% Ser:
7
0
0
0
7
0
0
7
0
0
0
7
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
40
7
0
0
0
0
0
0
% T
% Val:
7
7
0
0
0
0
0
7
40
40
0
0
0
47
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
7
20
7
0
0
0
0
% Y
% Spaces:
60
60
60
47
0
0
0
0
0
0
0
0
0
0
0
% _